Kisspeptin-10 is a synthetic peptide used to regulate reproductive hormones by stimulating the release of GnRH, supporting fertility and hormonal balance.
Overview
Kisspeptin-10 is a short-chain peptide derived from the natural kisspeptin protein, which plays a critical role in initiating the release of gonadotropin-releasing hormone (GnRH). This action, in turn, stimulates the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), essential for reproductive function.
It is being explored as a potential therapeutic agent in fertility treatments, especially for individuals experiencing delayed puberty, infertility, or hormonal imbalances. Kisspeptin-10 offers a more natural method of stimulating the reproductive axis compared to traditional hormone therapies.
Research
Clinical research has demonstrated that Kisspeptin-10 can effectively induce the release of GnRH and subsequently LH and FSH in both men and women. Trials have shown promise in using it to trigger ovulation and support sperm production without the risks associated with conventional hormone injections.
Further studies are ongoing to assess Kisspeptin-10’s role in treating conditions such as hypothalamic amenorrhea and polycystic ovary syndrome (PCOS). Its targeted mechanism may offer fewer side effects and improved outcomes compared to older fertility treatments.
Reviews
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