HMG is a fertility medication containing hormones that stimulate the ovaries to produce multiple eggs, commonly used in assisted reproductive treatments.
Overview
HMG is a combination of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), extracted from the urine of postmenopausal women. It helps stimulate ovarian follicle development, promoting the maturation of eggs for ovulation.
It is widely used in fertility treatments such as in vitro fertilization (IVF) and other assisted reproductive technologies (ART) to enhance chances of conception, especially in women who have difficulty ovulating naturally.
Research
Clinical studies have demonstrated that HMG effectively induces ovulation in women with infertility due to various causes, including polycystic ovary syndrome (PCOS) and hypogonadotropic hypogonadism. It improves follicular growth and increases pregnancy rates when used in controlled ovarian stimulation protocols.
Research continues to optimize dosing regimens and minimize side effects like ovarian hyperstimulation syndrome (OHSS). Innovations in recombinant gonadotropins are also being explored as alternatives to urinary-derived products like HMG.
Reviews
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